Drug – bio-affecting and body treating compositions – Plant material or plant extract of undetermined constitution... – Containing or obtained from a root – bulb – tuber – corm – or...
Reexamination Certificate
2011-04-05
2011-04-05
Hoffman, Susan C (Department: 1655)
Drug, bio-affecting and body treating compositions
Plant material or plant extract of undetermined constitution...
Containing or obtained from a root, bulb, tuber, corm, or...
Reexamination Certificate
active
07919127
ABSTRACT:
This invention relates to Pulsatillae Radix extract for improving brain functions. More specifically, this invention relates to Pulsatillae Radix extract, its active fractions and a pharmaceutical product and a health food containing the same respectively having a protective activity against neurotoxicity and a growth inhibitory effect induced by beta-amyloid, an anti-oxidizing effect, a neuron proliferating effect and improving memory thereby effective in improving brain functions such as Mild Cognitive Impairment and dementia.
REFERENCES:
patent: 10-2000-0074182 (2000-12-01), None
patent: 10-2002-0018695 (2002-03-01), None
patent: 10-2005-0023711 (2005-03-01), None
patent: 10-2005-0023712 (2005-03-01), None
patent: WO 2004/069263 (2004-08-01), None
Pulsatillapatens website (http://web.archive.org/web/20040826092936/http://montana.plant-life.org/species/pulsa—pate.htm—internet archived version from Aug. 2004).
Ye (Phytochemistry (1996), vol. 42, pp. 799-802).
Gao, Xiang-Dong et al.: “Pulsatilloside A and Anemoside A3Protect PC12 Cells from Apoptosis Induced by Sodium Cyanide and Glucose Deprivation”,Planta Med2003; 69; pp. 171-174.
Cheon, Seon Ah et al.: “The Anti-Inflammatory and Analgesic Actions of the Root ofPulsatilla koreana”, The Journal of Applied Pharmacology, 8, pp. 207-212 (2000). Article Is in Korean however an English translation of the Abstract of the article appears on the first page.
Choi Wonrack
Han Chang-kyun
Im Guang-Jin
Jung ChilMann
Kim bongcheol
Frommer & Lawrence & Haug LLP
Hoffman Susan C
Santucci Ronald R.
SK Chemicals Co. Ltd.
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