Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Reexamination Certificate
2004-12-01
2009-08-18
Vivlemore, Tracy (Department: 1635)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
C514S558000, C536S024500, C424S468000, C424S494000
Reexamination Certificate
active
07576067
ABSTRACT:
Delayed release oral pharmaceutical formulations and methods for enhanced intestinal drug absorption. The formulation comprises a first population of carrier particles comprising a drug and a penetration enhancer which are released at a first location in the intestine, and a second population of carrier particles comprising a penetration enhancer and a delayed release coating or matrix. This penetration enhancer is released at a second location in the intestine downstream from the first location and enhances absorption of the drug when it reaches the second location.
REFERENCES:
patent: 4713243 (1987-12-01), Schiraldi et al.
patent: 4773907 (1988-09-01), Urquhart et al.
patent: RE33093 (1989-10-01), Schiraldi et al.
patent: 4948580 (1990-08-01), Browning
patent: 5192802 (1993-03-01), Rencher
patent: 5314915 (1994-05-01), Rencher
patent: 5330761 (1994-07-01), Baichwal
patent: 5364634 (1994-11-01), Lew
patent: 5462728 (1995-10-01), Blank et al.
patent: 5462749 (1995-10-01), Rencher
patent: 5472704 (1995-12-01), Santus et al.
patent: 5508040 (1996-04-01), Chen
patent: 5514788 (1996-05-01), Bennett et al.
patent: 5554380 (1996-09-01), Cuca et al.
patent: 5595978 (1997-01-01), Draper et al.
patent: 5614222 (1997-03-01), Kaplan
patent: 5629001 (1997-05-01), Michael et al.
patent: 5653959 (1997-08-01), Tournier et al.
patent: 5670138 (1997-09-01), Venema et al.
patent: 5670163 (1997-09-01), Cuca et al.
patent: 5672359 (1997-09-01), Digenis et al.
patent: 5750136 (1998-05-01), Scholz et al.
patent: 5770627 (1998-06-01), Inoue et al.
patent: 5783193 (1998-07-01), Michael et al.
patent: 5801154 (1998-09-01), Baracchini et al.
patent: 5814336 (1998-09-01), Kelm et al.
patent: 5840329 (1998-11-01), Bai
patent: 5849322 (1998-12-01), Ebert et al.
patent: 5876742 (1999-03-01), Cochrum et al.
patent: 5877309 (1999-03-01), McKay et al.
patent: 5955502 (1999-09-01), Hansen et al.
patent: 5989535 (1999-11-01), Nayak
patent: 6080580 (2000-06-01), Baker et al.
patent: 6096722 (2000-08-01), Bennett et al.
patent: 6117450 (2000-09-01), Dittgen et al.
patent: 6120807 (2000-09-01), Gombotz et al.
patent: 6123965 (2000-09-01), Jacob et al.
patent: 6130217 (2000-10-01), Arnold et al.
patent: 6156348 (2000-12-01), Santos et al.
patent: 6200604 (2001-03-01), Pather et al.
patent: 6207197 (2001-03-01), Illum et al.
patent: 6217908 (2001-04-01), Mathiowitz et al.
patent: 6228383 (2001-05-01), Hansen et al.
patent: 6242004 (2001-06-01), Rault
patent: 6248720 (2001-06-01), Mathiowitz et al.
patent: 6274175 (2001-08-01), Gombotz et al.
patent: 6280770 (2001-08-01), Pather et al.
patent: 6303147 (2001-10-01), Gilis
patent: 6309853 (2001-10-01), Freidman et al.
patent: 6355276 (2002-03-01), Illum et al.
patent: 6368586 (2002-04-01), Jacob et al.
patent: 6375963 (2002-04-01), Repka et al.
patent: 6387408 (2002-05-01), Illum et al.
patent: 6391335 (2002-05-01), Pather et al.
patent: 6458383 (2002-10-01), Chen et al.
patent: 6500453 (2002-12-01), Brey et al.
patent: 0 250 187 (1987-12-01), None
patent: 0 449 782 (1991-10-01), None
patent: 0 452 268 (1991-10-01), None
patent: 0 516 141 (1992-12-01), None
patent: 0 526 826 (1993-02-01), None
patent: WO 8502092 (1985-05-01), None
patent: WO 91/19486 (1991-12-01), None
patent: WO 95/26715 (1995-10-01), None
patent: WO 97/13528 (1997-04-01), None
patent: WO 97/24109 (1997-07-01), None
patent: WO 98/49348 (1998-11-01), None
patent: WO 99/01579 (1999-01-01), None
patent: WO 99/60012 (1999-11-01), None
patent: WO 00/35418 (2000-06-01), None
patent: WO 00/41740 (2000-07-01), None
patent: WO 00/47644 (2000-08-01), None
patent: WO 00/66089 (2000-11-01), None
patent: WO 02/41765 (2002-05-01), None
patent: WO 02/060415 (2002-08-01), None
Robertson, D., “Crohn's trial shows the pros of antisense,” Nature Biotechnol., Mar. 1997, 15, p. 209.
Ahmed, A. et al., “Bioadhesive microdevices with multiple reservoirs: a new platform for oral drug delivery”, Journal of Controlled Release, 2002, 81, 291-306.
Duchene, D. et al., “Bioadhesion of solid oral dosage forms, why and how?”, European Journal of Pharmaceutics and Biopharmaceutics, 1997, 44, 15-23.
Gu, J-M. et al., “Binding of acrylic polymers to mucin/epithelial surfaces: structure-property relationships” CRC Critical Reviews in Therapeutic Drug Carrier Systems, 1988, 5(1), 21-67.
Kue, P.Y.P. et al., “Novel systems for controlled delivery of macromolecules”, Critical Reviews in Eukaryotic Gene Expressions, 1996, 6(1), 59-73.
Lehr, C-M. “Bioadhesion technologies for the delivery of peptide and protein drugs to the gastrointestinal tract”, Critical Reviews in Therapeutic Drug Carrier Systems, 1994, 11(2&3), 119-160.
Muranishi S. (Critical Reviews in Therapeutic Drug Carrier Systems; 1990 vol. 7, pp. 1- 33) Absorption Enhancers.
Ponchel, G. et al., “Specific and non-specific bioadhesive particulate systems for oral delivery to the gastrointestinal tract”, Advanced Drug Delivery Reviews, 1998, 34, 191-219.
Shimoda, J. et al., “Bioadhesive characteristics of chitosan microspheres to the mucosa of rat small intestine” Drug Development and Industrial Pharmacy, 2001, 27(6), 567-576.
Woodley, J. “Bioadhesion: New possibilities for drug administration?”, Clin Pharmacokinet, 2001, 40(2), 77-84.
Geary Richard S.
Hardee Gregory E.
Tillman Lloyd G.
Weinbach Susan
Isis Pharmaceuticals , Inc.
Isis Pharmaceuticals Inc. Patent Department
Vivlemore Tracy
LandOfFree
Pulsatile release compositions and methods for enhanced... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Pulsatile release compositions and methods for enhanced..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pulsatile release compositions and methods for enhanced... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4118895