Pulmonary surfactant protein fragments

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

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514 13, 514 14, 514 15, 530324, 530326, 530327, 530328, A61K 3800, C07K 710, C07K 708

Patent

active

057536210

ABSTRACT:
This invention discloses that certain fragments of a pulmonary surfactant protein exhibit unexpected surface activity. These protein fragments are useful in preparing formulations for the treatment of respiratory distress syndrome.

REFERENCES:
patent: 4234475 (1980-11-01), Sokol
patent: 4861756 (1989-08-01), Jackson
patent: 5055553 (1991-10-01), Jacobs et al.
patent: 5164369 (1992-11-01), Cochrane et al.
patent: 5238920 (1993-08-01), Sarin et al.
patent: 5510333 (1996-04-01), Angelastro et al.
"Surfactant Chemical Composition and Biophysical Activity in Acute Respiratory Distress Syndrome", Gregory et al., The American Society for Clinical Investigation, Inc., vol. 88, pp. 1976-1981.
"Enzymic Inactivation of Oxytocin, III, Desthiooxytocin And S,S'-Debenzyldihydrooxytocin as Oxytocinase Inhibitors and Substrates", Berankova et al, Czechoslovak Academy of Science, vol. 26, pp. 2557-2561, 1961.
"Conformation of Biopolymers", Ramachandran, Academic Press Inc. (London) Ltd., vol. 1, pp. 215-216, 1967.
"The Role of Sulfur in Proteins", Liu, The Proteins, vol. III, pp. 239 and 255, 1977.
Preparation of S,S'-Dibenzyloxytocin and Its Reconversion to Oxytocin, Gordon, et al, P.S.E.B.M., V. 84, 1953.
"cDNA and deduced amino acid sequence of human pulmonary surfactant-associated proteolipid SPL(Phe)", Glasser et al, Biochemistry, vol. 84, 1987, pp. 4007-4011.
"Interactions with Peptide Paradigms for the Sufactant Protein SP-B+", Vincent et al, Biochemistry, 1991 30, 8395-8401.
"Human surfactant polypeptide SP-B Disulfide bridges, C-terminal end, and peptide analysis of the airway form", Johansson et al, Elsevier Science Puclishers B.V., vol. 301, No. 2, 165-167, 1992.
"Exogenous Surfactant for Human Lung Disease", Taeusch, et al. American Rev.Respiratory Diseases, vol. 128, 791-794, 1983.
"Biophysical and biological activity of a synthetic 8.7 kDa hydrophobic pulmonary surfactant protein SP-B", Proc. National Acad. Science, vol. 87, pp. 2633-2637, 1990.
"Pulmonary Surfactant Therapy", The New England Journal of Medicine, Drug Therapy-Jobe, vol. 328, No. 12, pp. 861-868.

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