PTP 1D: a novel protein tyrosine phosphatase

Chemistry: molecular biology and microbiology – Spore forming or isolating process

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4351723, 4353201, 4352523, 43525233, 435 4, 435195, 935 14, 935 20, 935 24, 935 32, 935 70, 935 71, 935 72, 935 73, 536 232, 536 231, C12N 506, C07H 2104

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055893759

ABSTRACT:
A novel protein tyrosine phosphatase is the protein designated PTP 1D. The PTP 1D protein may be produced by recombinant means, for example using a nucleic acid construct encoding the protein as provided herein. Also disclosed is an antibody specific for an epitope of PTP 1D, protein. Methods for identifying compounds which bind to a PTP 1D protein and inhibit or stimulate its enzymatic activity, pharmaceutical compositions comprising PTP 1D, and methods for treating a disease associated with PTP 1D protein using such compositions, are provided.

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