Pteridine compounds for the treatment of psoriasis

Organic compounds -- part of the class 532-570 series – Organic compounds – Four or more ring nitrogens in the bicyclo ring system

Reexamination Certificate

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Reexamination Certificate

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06875868

ABSTRACT:
The invention provides pteridine compounds of formula (I), processes and intermediates used in their preparation, pharmaceutical compositions containing them and their use in therapy. Formula (I) in which A is a group of formula (a) or (b).

REFERENCES:
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patent: 0 447 324 (1991-09-01), None
patent: WO 0039129 (2000-07-01), None
patent: WO 0045800 (2000-08-01), None
patent: WO 0119825 (2001-03-01), None
Patent Abstracts of Japan, abstract of JP-5-202047 A (Chugai Pharmaceut. Co. Ltd.) Aug. 10, 1993.
Manfred Ott et al., “Zur Synthese des 4-Amino-7-oxo-7, 8-dihydropteridin-N-8-beta-D-ribofuranosids—ein strukturanaloges Nucleosid des Adenosins”, vol. 107, Chem.Ber., 339-361 (1974).
Manfred Ott et al., “4-Amino-7, 8-Dihydro-2-(Methylmercapto)-8-beta, -D-ribofuranosylpteridin-7-One, Modified Fusion Reaction with Trimethylsilylated Pteridine Derivatives”, vol. 2, Nucl. Acid. Chem., 735-739 (1978).
Leonidas Kiriasis et al., “Synthesis and Properties of New Pteridine Nucleosides”, vol. 4, Dev. Biochem., 49-53 (1978).

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