Pt(IV) complexes as anti-tumor agents

Details Pt(IV) complexes as anti-tumor agents Pt(IV) complexes as anti-tumor agents

1991-07-01

1993-09-14

Lewis, Michael

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heavy metal containing doai

A61K 3324

Patent

active

052449190

ABSTRACT:
A Pt(IV) complex of the formula ##STR1## wherein A and A' are NH.sub.3 or an amino group; R and R.sup.1 are hydrogen, alkyl, alkenyl, aryl, aralkyl, alkylamino or alkoxy or functionalized derivatives thereof; and X is halogen or alkyl mono- or dicarboxylate. The complexes have high antitumor activity, particularly when administered orally.

REFERENCES:
patent: 5072011 (1991-12-01), Abrams et al.

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