Organic compounds -- part of the class 532-570 series – Organic compounds – Heavy metal containing
Patent
1990-10-25
1991-12-10
Straub, Gary P.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heavy metal containing
C07F 1500, A61K 31295
Patent
active
050720112
ABSTRACT:
A Pt(IV) complex of the formula ##STR1## wherein A and A' are NH.sub.3 or an amino group; R and R' are hydrogen, alkyl, alkenyl, aryl, aralkyl, alkylamino or alkoxy or functionalized derivatives thereof; and X is halogen or alkyl mono- or dicarboxylate. The complexes have high antitumor activity, particularly when administered orally.
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Abrams Michael J.
Giandomenico Christen
Murrer Barry A.
Vollano Jean F.
Hendrickson Stuart L.
Johnson Matthey Inc.
Straub Gary P.
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