Psyllium tablet composition, method of manufacture and method of

Details Psyllium tablet composition, method of manufacture and method of Psyllium tablet composition, method of manufacture and method of

1987-12-09

1991-03-12

Rollins, John W.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424464, 424465, 424474, 4241951, 514892, A61K 936, A61K 920, A61K 3578

Patent

active

049992007

ABSTRACT:
A psyllium composition in tablet form is provided having a wetting agent, a disintegrant and a binding agent. In one embodiment, the wetting agent is polysorbate 80, the binding agent is polyvinyl pyrrolidone and the dry binding agent and disintegrant is microcrystalline cellulose. Calcium carbonate may also be added to serve as a disintegrant in HCL. The tablets are manufactured by mixing the psyllium powder with a solution of povidone and polysorbate 80. Microcrystalline cellulose may be added either during or after granulation. After mixing, the composition is compressed into tablet form. The mixing of the ingredients in specific quantities allows a tablet to be manufactured that is both resistant to fracture and at the same time disintegrates easily and quickly in the gastrointestinal tract of the patient.

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patent: 4683256 (1987-07-01), Porter et al.
patent: 4689229 (1987-08-01), Banik

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