Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Food or edible as carrier for pharmaceutical
Patent
1995-06-02
1997-02-11
Bawa, Raj
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Food or edible as carrier for pharmaceutical
424 781, 424 7801, 424489, A61K 31785
Patent
active
056018371
ABSTRACT:
This invention relates to an oral pharmaceutical composition comprising from about 1% to 75%, by weight, psyllium husk with more than about 97% of the psyllium husk being smaller than about 100 mesh screen; from about 1% to 65%, by weight, cholestyramine; and wherein the ratio of the psyllium husk to the cholestyramine is from about 3:1 to about 1:2, and wherein the composition delivers from 1 g to 30 g of the psyllium husk and from about 4 g to about 30 g of the cholestyramine daily when the composition is taken orally in one or more doses.
REFERENCES:
patent: 3148114 (1964-09-01), Fahrenbach et al.
patent: 3499960 (1970-03-01), Macek et al.
patent: 3923972 (1975-12-01), Fields et al.
patent: 3974272 (1976-08-01), Polli et al.
patent: 4321263 (1982-03-01), Powell et al.
patent: 4459280 (1984-07-01), Colliopoulos et al.
patent: 4511561 (1985-04-01), Maddaus et al.
patent: 4548806 (1985-10-01), Colliopoulos et al.
patent: 4565702 (1986-01-01), Morley et al.
patent: 4619831 (1986-10-01), Sharma
patent: 4747881 (1988-05-01), Shaw et al.
patent: 4778676 (1988-10-01), Yang et al.
patent: 4790991 (1988-12-01), Shaw et al.
patent: 4818539 (1989-04-01), Shaw et al.
patent: 4824672 (1989-04-01), Day et al.
patent: 4828842 (1989-05-01), Furst et al.
patent: 4843098 (1989-06-01), Shaw et al.
patent: 4849222 (1989-07-01), Broaddus
patent: 4882157 (1989-11-01), Yang et al.
patent: 4883788 (1989-11-01), Day et al.
patent: 4895723 (1990-01-01), Amer et al.
patent: 4950689 (1990-08-01), Yang et al.
patent: 4996051 (1991-02-01), Meer et al.
patent: 5009916 (1991-04-01), Colliopoulos et al.
patent: 5023245 (1991-06-01), Kuhrts
patent: 5048760 (1991-09-01), Barbera et al.
patent: 5422101 (1995-06-01), Daggy et al.
Anderson et al., "Hypocholesterolemic Effects of Psyllium Mucilloid for Hypercholesterolemic Men", Fed. Proceed., 46 (3), p. 877 (1987).
Anderson et al. "Dietary Fiber: Hyperlipidemia, Hypertension and Coronary Disease", Amer. J. Gastroent., 81, pp. 907-919 (1986).
Fagerberg, "The Effects of a Bulk Laxative (Metamucil.RTM.) on Fasting Blood Glucose, Serum Lipids and Other Variables in Constipated Patients with Non-Insulin Dependent Adult Diabetes", Curr. Thera. Res., vol. 31 (2), pp. 166-172 (1982).
Forman et al., "Increased Excretion of Fecal Bile Acids by an Oral Hydrophilic Colloid", Proc. Soc. Exp. Biol. Med. vol. 120(3), pp. 1060-1063 (1968).
Beher et al., "The Effect of Psyllium Hydrocolloid and Cholestyramine on Hepatic Bile Lipid Composition in Man", Henry Ford Hospital Medical Journal, 21(1), pp. 21-30 (1973).
Merck Index, 10th Edition, Merck & Co. Inc. (1983), No. 2182: "Cholestyrramine Resin".
Stein, "Management of Hypercholesterolemia, Approach to Diet and Drug Therapy", The Americal Journal of Medicine, vol. 87 (4A), pp. 20S-27S (1989).
Questran.RTM. (Bristol-Myers) and Cholybars.RTM. (Parke Davis), Physicians Desk Reference, 44th Edition, pp. 726-729 and 1595-1597 (1990).
Metamucil.RTM., Physician's Desk Reference for Non-Prescription Drugs, 9th Edition (1988), Medical Economics Company, Inc., pp. 642-644.
Colliopoulos John A.
Kardouche Nabil G.
Bawa Raj
Mohl Douglas C.
Poland Mary Catherine
The Procter & Gamble & Company
Zerby Kim William
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