Psyllium cholestyramine compositions with improved palatability

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Food or edible as carrier for pharmaceutical

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

424 781, 424 7801, 424489, A61K 31785

Patent

active

056018371

ABSTRACT:
This invention relates to an oral pharmaceutical composition comprising from about 1% to 75%, by weight, psyllium husk with more than about 97% of the psyllium husk being smaller than about 100 mesh screen; from about 1% to 65%, by weight, cholestyramine; and wherein the ratio of the psyllium husk to the cholestyramine is from about 3:1 to about 1:2, and wherein the composition delivers from 1 g to 30 g of the psyllium husk and from about 4 g to about 30 g of the cholestyramine daily when the composition is taken orally in one or more doses.

REFERENCES:
patent: 3148114 (1964-09-01), Fahrenbach et al.
patent: 3499960 (1970-03-01), Macek et al.
patent: 3923972 (1975-12-01), Fields et al.
patent: 3974272 (1976-08-01), Polli et al.
patent: 4321263 (1982-03-01), Powell et al.
patent: 4459280 (1984-07-01), Colliopoulos et al.
patent: 4511561 (1985-04-01), Maddaus et al.
patent: 4548806 (1985-10-01), Colliopoulos et al.
patent: 4565702 (1986-01-01), Morley et al.
patent: 4619831 (1986-10-01), Sharma
patent: 4747881 (1988-05-01), Shaw et al.
patent: 4778676 (1988-10-01), Yang et al.
patent: 4790991 (1988-12-01), Shaw et al.
patent: 4818539 (1989-04-01), Shaw et al.
patent: 4824672 (1989-04-01), Day et al.
patent: 4828842 (1989-05-01), Furst et al.
patent: 4843098 (1989-06-01), Shaw et al.
patent: 4849222 (1989-07-01), Broaddus
patent: 4882157 (1989-11-01), Yang et al.
patent: 4883788 (1989-11-01), Day et al.
patent: 4895723 (1990-01-01), Amer et al.
patent: 4950689 (1990-08-01), Yang et al.
patent: 4996051 (1991-02-01), Meer et al.
patent: 5009916 (1991-04-01), Colliopoulos et al.
patent: 5023245 (1991-06-01), Kuhrts
patent: 5048760 (1991-09-01), Barbera et al.
patent: 5422101 (1995-06-01), Daggy et al.
Anderson et al., "Hypocholesterolemic Effects of Psyllium Mucilloid for Hypercholesterolemic Men", Fed. Proceed., 46 (3), p. 877 (1987).
Anderson et al. "Dietary Fiber: Hyperlipidemia, Hypertension and Coronary Disease", Amer. J. Gastroent., 81, pp. 907-919 (1986).
Fagerberg, "The Effects of a Bulk Laxative (Metamucil.RTM.) on Fasting Blood Glucose, Serum Lipids and Other Variables in Constipated Patients with Non-Insulin Dependent Adult Diabetes", Curr. Thera. Res., vol. 31 (2), pp. 166-172 (1982).
Forman et al., "Increased Excretion of Fecal Bile Acids by an Oral Hydrophilic Colloid", Proc. Soc. Exp. Biol. Med. vol. 120(3), pp. 1060-1063 (1968).
Beher et al., "The Effect of Psyllium Hydrocolloid and Cholestyramine on Hepatic Bile Lipid Composition in Man", Henry Ford Hospital Medical Journal, 21(1), pp. 21-30 (1973).
Merck Index, 10th Edition, Merck & Co. Inc. (1983), No. 2182: "Cholestyrramine Resin".
Stein, "Management of Hypercholesterolemia, Approach to Diet and Drug Therapy", The Americal Journal of Medicine, vol. 87 (4A), pp. 20S-27S (1989).
Questran.RTM. (Bristol-Myers) and Cholybars.RTM. (Parke Davis), Physicians Desk Reference, 44th Edition, pp. 726-729 and 1595-1597 (1990).
Metamucil.RTM., Physician's Desk Reference for Non-Prescription Drugs, 9th Edition (1988), Medical Economics Company, Inc., pp. 642-644.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Psyllium cholestyramine compositions with improved palatability does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Psyllium cholestyramine compositions with improved palatability, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Psyllium cholestyramine compositions with improved palatability will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-339855

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.