Psychotropic heterobicycloalkylpiperazine derivatives

Details Psychotropic heterobicycloalkylpiperazine derivatives Psychotropic heterobicycloalkylpiperazine derivatives

1992-03-02

1993-04-27

Rizzo, Nicholas S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

544235, 544295, C07D491048, C07D49504, C07D51900

Patent

active

052063658

ABSTRACT:
A series of psychotropic heterobicycloalkylpiperazine derivatives having the structure ##STR1## wherein V is a 3- or 4-membered unsaturated chain, containing all carbon atoms when 4-membered, or when a 3-membered chain, V contains an oxygen or sulfur atom as one of the members; R is H or C.sub.1-4 alkyl; W is CH, N, CH.sub.2, or a chemical bond; X is CH, N, SO.sub.2, or CO, with the proviso that both W and X cannot simultaneously be N; and Z is a heteroaromatic ring system. These compounds are useful antipsychotic and/or anxiolytic agents.

REFERENCES:
patent: 4670560 (1987-06-01), Press et al.
patent: 4703120 (1987-10-01), Press et al.
patent: 4835157 (1989-05-01), Press et al.
patent: 5001130 (1991-03-01), New et al.

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