Psoriasin expression by breast epithelial cells

Details Psoriasin expression by breast epithelial cells Psoriasin expression by breast epithelial cells

2002-12-30

2008-12-16

Yu, Misook (Department: 1642)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

C435S006120, C436S501000, C436S518000

Reexamination Certificate

active

07465553

ABSTRACT:
The invention features methods of diagnosing high grade ductal carcinoma in situ (DCIS) These methods involve measuring: (1) the level of HID-5 in a body fluid (e.g., blood or urine) of a subject suspected of having, or at risk of having, high grade DCIS; or (2) the level of HID-5 gene expression in breast tissue from a subject suspected of having, or at risk of having, high grade DCIS. The invention also embodies a method of inhibiting expression of HID-5 protein in DCIS cells and methods of treating a subject suspected of having, or at risk of having, high grade DCIS.

REFERENCES:
patent: WO 00/26668 (2000-05-01), None
patent: WO 00/55629 (2000-09-01), None
patent: WO 01/87238 (2001-11-01), None
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