Pseudotyped retroviral vectors

Details Pseudotyped retroviral vectors Pseudotyped retroviral vectors

2005-03-08

2005-03-08

Guzo, David (Department: 1636)

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Genetically modified micro-organism, cell, or virus

C424S093100, C424S093600, C435S325000, C435S366000, C435S320100, C435S455000, C435S456000

Reexamination Certificate

active

06863884

ABSTRACT:
The present invention provides pseudotyped retroviral vectors and packaging systems and methods of using such vectors for retroviral-mediated gene transfer. In particular, the present invention provides a retroviral packaging system that comprises at least two vectors: a first vector comprising a gag, a pol, or gag and pol genes; and a second vector comprising a functionally modified or heterologous envelope gene, for example, a baculovirus envelope gene.

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