Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Glycoprotein – e.g. – mucins – proteoglycans – etc.
Patent
1989-07-21
1993-03-23
Moskowitz, Margaret
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Glycoprotein, e.g., mucins, proteoglycans, etc.
530806, 530350, 424 89, C07K 1514
Patent
active
051965160
ABSTRACT:
The present invention is concerned with a pseudorabies virus (PRV) vaccine comprising a polypeptide of the PRV glycoprotein gII or a fragment thereof which was shown to be the site of interaction of PRV neutralizing antibodies. Vector vaccines capable to express a polynucleotide fragment coding for such a polypeptide also form part of the present invention.
REFERENCES:
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Robbins et al. 1987. J. Virol. 61(9):2691-2701.
Lerner, R. A. 1982. Natur. 299:592-596.
Simon et al. 1989. J. gen Virol. 70:1239-1246.
Halling, S. M. 1985. Molecular Genetics, Inc. (Meet., 54) (Dialog File 357, DBA Accession No.: 86-08964. Abstract).
Mettenleiter et al. 1986. Virology 152:66-75.
Wunner et al. 1985. Virology 140:1-12.
Lukacs Noemi
Mettenleiter Thomas C.
Rziha Hanns J.
Schreurs Christa S.
Simon Artur J.
Akzo N.V.
Blackstone William M.
Bobrowicz Donna
Furman Keith C.
Moskowitz Margaret
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