Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor
Patent
1992-11-23
1994-01-25
Schwartz, Richard A.
Chemistry: molecular biology and microbiology
Micro-organism, per se ; compositions thereof; proces of...
Bacteria or actinomycetales; media therefor
435 691, 4351723, 4353201, 424 93N, 536 2371, C12N 121
Patent
active
052815323
ABSTRACT:
Novel biological pesticides are prepared by introducing into a microorganism the genetic capability to produce a heterologous pesticide, wherein the microorganism is capable of proliferating in the rhizosphere or phylloplane in competition with wild-type microorganisms. A gene capable of expressing a polypeptide is introduced into the microorganism under conditions which allow for stable maintenance and expression of the gene, without significantly diminishing the ability of the microorganism to compete in the environment. Preferred microorganisms provide for the maintenance and protection from degradation of the polypeptide pesticide.
REFERENCES:
Faust et al, 1981, In Genetic Engineering in the Plant Sciences, N. J. Panopoulos (ed), Praeger, N.Y., pp. 225-252.
Bogdasarian et al. 1981 Gene 16:237-241.
Hinnen et al 1978 PNAS 75(4):1929-1933.
Held et al 1982 PNAS 79:6065-6069.
N. J. Panopoulos, 1986, Tactics and Feasibility of Genetic Engineering of Biocontrol Agents; In: Fokkema and van den Heuvel (eds), Microbiology of the Phyllosphere, Cambridge Univ. Press, pp. 312-332.
Edwards David L.
Gaertner Frank H.
Rammler David H.
LeGuyader J.
Mycogen Corporation
Schwartz Richard A.
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