Protozoal antigen

Details Protozoal antigen Protozoal antigen

1986-07-31

1989-06-06

Hazel, Blondel

Drug, bio-affecting and body treating compositions

Lymphokine

530350, 530412, 530413, 435 68, 43524026, A61K 39015, C12N 500, C07K 1504

Patent

active

048370169

ABSTRACT:
Protection inducing antigens or parasites of the genus Plasmodium are described. The antigens have an apparent molecular weight of 1.8 to 2.5.times.10.sup.5 and are associated with the membranes of the erythrocytic schizont forms of the parasite. The antigens may be incorporated into vaccines and used for the inducing of immunity into susceptible vetebrate hosts including humans. Methods for the preparation of the antigens are also described.

REFERENCES:
Kilejian, A., J. Exp. Med., vol. 151, pp. 1534-1538, 1980.
Kilejian, A., Proc. Natl. Acad. Sci., vol. 77, pp. 3695-3699, 1980.
Chemical Abstracts, vol. 93, p. 675, Abst. No. 43548x, 1980.
Chemical Abstracts, vol. 93, p. 676, Abst. No. 43561, 1980.
Penin, L. H., et al., Nature, vol. 289, pp. 301-303, 1981.
Freeman et al., Host. Invader Interplay, Ed. H. Van den Bosche, Elsaveir, North Holland, Biomedical Press, pp. 121-124, 1980.
Freeman et al., Experimental Parasitology, vol. 52, pp. 18-24, 1981.

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