Protozoacidal activity of phenothiazines

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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A61K 3154

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active

044078005

ABSTRACT:
A method of treating or protecting against parasitic diseases caused by members of the protozoan family Trypanosomatidae comprising administering to a mammal a phenothiazine drug. This represents a new use of the phenothiazine compounds.

REFERENCES:
Current Therapy, H. F. Conn, W. B. Saunders Co., Phila., Lond., Tor., 1981, pp. 39-40.
The Pharmacological Basis of Theraputics, Goodman et al., MacMil., 1980, pp. 417-418.
Chem. Abstr., vol. 87, 1977, p. 585, Ab. No. 152101t, Savelli et al., Derivatives of 2-phenothiazine . . . .
Merck Index, 9th ed., Merck Co., p. 850, No. 6363.
Medical Parasitology in the Tropics, Nnochiri, E., Oxford Press, Lond., 1975, p. 123.

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