Proteins useful in the regulation of .kappa.B-containing genes

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues

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4351723, 935 11, 935 34, 935 36, C07K 1400

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active

RE0358231

ABSTRACT:
Proteins, and corresponding DNA and RNA sequences, useful for the regulation of expression of .kappa.B-containing genes are disclosed. These proteins are useful to either stimulate or inhibit the expression of .kappa.B-containing genes. Proteins stimulating the expression of .kappa.B-containing genes have an amino acid sequence at least 80% identical to the amino acid sequence of from position 1 to position 374 of expression of .kappa.B-containing genes have sequences either at least 80% identical to the amino acid sequence of from position 407 to the carboxyl identical to the amino sequence of either from position 1 to 100 sor from

REFERENCES:
Ansorge et al., Nucleic Acids Res., vol. 15. pp. 4593-4602, 1987.
Brumbaugh et al., PNAS, vol. 85, pp. 5610-5614, 1988.
Cathcart et al., Nature, vol. 347, p. 310, 1990.
Connell et al., Biotechniques, vol. 5, pp. 342-344, 1987.
Lee et al., Nucleic Acids Res., vol. 20, pp. 2471-2483, 1992.
Prober et al., Science, vol. 238, pp. 336-341, 1987.
Sanger et al., PNAS, vol. 74, pp. 5463-5467, 1977.
Smith et al., Nucleic Acids Res., vol. 13, pp. 2399-2412, 1985.
Smith et al., Nature, vol. 321, pp. 674-679, 1986.
Franza et al., Nature vol. 330, pp. 391-395 (1987).
Ghash et al., Cell vol. 62, pp. 1019-1029 (1990).
Publication--"Tampering with Transcription", by Gary J. Nabel, News and Views, Nature, vol. 350, Apr. 25, 1991, p. 658.
Aids Research Reviews, vol. 1, Chapter 2, by Gary J. Nable, Marcel Dekker, Inc., New York, Basel, Hong Kong, pp. 21-34, Chapter 2 entitled "Cellular Regulation of Human Immunodeficiency Virus Gene Expression".
Helene et al., Biochimica et Biophysica Acta., vol. 1049, pp. 99-145 (1990) .

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