Proteins producing an altered immunogenic response and...

Details Proteins producing an altered immunogenic response and... Proteins producing an altered immunogenic response and...

2005-05-24

2005-05-24

Saunders, David (Department: 1644)

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

C424S094100, C424S094630, C424S094640, C424S184100, C424S275100, C435S212000, C435S219000, C435S220000, C435S221000, C435S222000, C435S223000, C435S224000, C435S225000

Reexamination Certificate

active

06897049

ABSTRACT:
The present invention relates to a novel methods and compositions for producing hyper and hypo allergenic compositions. Specifically, the present invention comprises neutralizing or reducing the ability of T-cells to recognize epitopes and thus prevent sensitization of an individual to the protein. Alternatively, T-cell epitopes are mutated to produce increased immunogenic reactions.

REFERENCES:
patent: 5268454 (1993-12-01), Barstad et al.
patent: 5500362 (1996-03-01), Robinson et al.
patent: 5712120 (1998-01-01), Rodriguez et al.
patent: 5801038 (1998-09-01), Bott et al.
patent: 5837517 (1998-11-01), Sierkstra et al.
patent: 6596525 (2003-07-01), Estell et al.
patent: 0251446 (1988-01-01), None
patent: 0 699 755 (1996-03-01), None
patent: WO 9210755 (1992-06-01), None
patent: WO 9616177 (1996-05-01), None
patent: 9634946 (1996-11-01), None
patent: WO 9634946 (1996-11-01), None
patent: WO9730148 (1997-08-01), None
patent: WO 9820116 (1998-05-01), None
patent: WO 9852976 (1998-11-01), None
patent: WO 9953038 (1999-10-01), None
patent: WO 9961637 (1999-12-01), None
patent: WO 0034317 (2000-06-01), None
Stedman's Medical Dictionary, 24th Edition, Williams & Wilkins, 1982.*
Copy of PCT partial search for PCT/US 01/30062.
*Gundlach et al., “Determination of T cell epitopes with random peptide libraries,”Journal of Immunological Methods, V. 192 (1996) pp. 149-155.
*Copy of PCT search report.
Graziano et al., “Enhancing the Immunogenicity of a Permissive Binding T Cell Epitope derived from the Simian Immunodeficiency Virus-Encoded Negative Regulatory Factor,”J. of Immun.,V. 149, No. 2, 1991, pp. 556-561.
Lipford et al., “Peptide engineering allows cytotoxic T-cell vaccination against human papilloma virus tumour antigen, E6”, Abstract, Database accession No. PREV199598171988.

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