Proteins producing an altered immunogenic response and...

Details Proteins producing an altered immunogenic response and... Proteins producing an altered immunogenic response and...

2005-01-04

2005-01-04

Saunders, David (Department: 1644)

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

C424S050000, C424S094100, C424S094400, C424S094600, C424S184100, C424S275100, C424S401000, C435S183000, C435S189000, C435S195000, C435S262000, C435S263000

Reexamination Certificate

active

06838269

ABSTRACT:
The present invention relates to a novel methods and compositions for producing hyper and hypo allergenic compositions. Specifically, the present invention comprises neutralizing or reducing the ability of T-cells to recognize epitopes and thus prevent sensitization of an individual to the protein. Alternatively, T-cell epitopes are mutated to produce increased immunogenic reactions. Moreover, naturally occuring proteins are provided.

REFERENCES:
patent: 5593877 (1997-01-01), King
patent: 5801038 (1998-09-01), Bott et al.
patent: 5837517 (1998-11-01), Sierkstra et al.
patent: 5951980 (1999-09-01), Collen
patent: 6495136 (2002-12-01), Weisgerber et al.
patent: 0 006 638 (1980-01-01), None
patent: 0 699 755 (1996-03-01), None
patent: WO 9210755 (1992-06-01), None
patent: WO 9505849 (1995-03-01), None
patent: WO 9616177 (1996-05-01), None
patent: WO 9634946 (1996-11-01), None
patent: WO 9730148 (1997-08-01), None
patent: WO 9820116 (1998-05-01), None
patent: WO 9852976 (1998-11-01), None
patent: WO 9906061 (1999-02-01), None
patent: WO 9953038 (1999-10-01), None
patent: 9953078 (1999-10-01), None
patent: WO 9961637 (1999-12-01), None
patent: WO 0034317 (2000-06-01), None
patent: 0034317 (2000-06-01), None
Herbert et al, Dictionary of Immunology—3rd ED., Blackwell Scientific Publications, 1985.*
Copy of PCT partial search for PCT/US 01/30062.
Graziano et al., “Enhancing the Immunogenicity of a Permissive Blinding T Cell Epitope derived from the Simian Immunodeficiency Virus-Encoded Negative Regulatory Factor,”J. of Immun., V. 149, No. 2, 1991, pp. 556-561.
Lipford et al., “Peptide engineering allows cytotoxic T-cell vaccination against human papiloma virus tumour antigen, E6”, Abstract, Database accession No. PREV199598171988.
Gundlach et al., “Determination of T cell epitopes with random peptide libraries,”Journal of Immunological Methods. V. 1992, (1996) pp. 149-155.

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