Proteins having hemolytic activity and genes encoding the...

Details Proteins having hemolytic activity and genes encoding the... Proteins having hemolytic activity and genes encoding the...

2007-10-16

2007-10-16

Mondesi, Robert B. (Department: 1656)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C435S069100, C435S320100, C435S325000

Reexamination Certificate

active

11024428

ABSTRACT:
Hemolytic proteins offer new approaches to drug development. The hemolytic proteins are obtained from a nematocyst ofCarybdea alata. Alternatively, the proteins may be recovered from cultured cells transfected with the sequence encoding the hemolytic protein ofCarybdea alata.

REFERENCES:
patent: 6653449 (2003-11-01), Nagai et al.
Nagai, et al. “Isolation and Characterization of a Novel Protein Toxin from the Hawaiian Box Jellyfish (Sea Wasp)Carybdea alata” Biochemistry Biophys. Res. Communication, 2000, 275, pp. 589-594.
Nagai, “Hajimete Akirakani sareta Kurage Doku no Kagakuteki Seijo” Bioscience to Industry, 2000, 58, 11, pp. 1797-1798.
Rottini, et al. “Purification and properites of a cytolytic toxin in venom of the jellyfishCarybdea marsupialis” Toxicon, 1995, 33, 3, pp. 315-326.

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