Protein with bone formation ability and process for its producti

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 15 to 23 amino acid residues in defined sequence

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530327, 530350, 514 12, 435 691, 536 235, C07K 14435, C07K 1451, C07K 14475, C07K 708

Patent

active

057566640

ABSTRACT:
The present invention provides the sequence of the novel bone-related protein OSF-2 which can be obtained from mammalian bone tissues. The invention further provides a method of production of OSF-2 by recombinant techniques.

REFERENCES:
Takeshita et al. Biochem J. (1993) 294 271-278.
Tezuka et al BBRC. (1990) 173 246-251.
Zinn, K., et al., Cell. "Sequence Analysis and Neuronal expression of fasciclin I in grasshopper and drosophila", vol. 53:577-587 (May 20, 1988).
Tezuka, K., et al., Biochemical and Biophysical Research Communications, "Isolation of mouse and human cDNA clones encoding a protein expressed specifically in osteoblasts and brain tissues," vol. 173(1) 246-251 (Nov. 30, 1990).
European Search Report for Application No. 93104650.2.

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