Protein temperature evaporation-controlled crystallization...

Single-crystal – oriented-crystal – and epitaxy growth processes; – Processes of growth from liquid or supercritical state – Having growth from a solution comprising a solvent which is...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C117S069000, C117S070000, C117S925000, C422S245100

Reexamination Certificate

active

10825179

ABSTRACT:
A temperature- and evaporation-controlled device for the crystallization of proteins from a protein-containing solution. The device comprises a compartment, such as a microcapillary tube, for holding the solution from which crystals are formed. The compartment is in communication with a cold generating unit, such as a cold finger, that maintains a temperature lower than the temperature of the compartment thereby causing de-watering of the solution. A vacuum pump can be attached to the device to reduce vapor pressure to further promote de-watering of the solution. The device can be used terrestrially or in a microgravity environment, such as in outer space, for formation of high quality protein crystals.

REFERENCES:
patent: 4755363 (1988-07-01), Fujita et al.
patent: 4886646 (1989-12-01), Carter et al.
patent: 5096676 (1992-03-01), McPherson et al.
patent: 5126115 (1992-06-01), Fujita et al.
patent: 5130105 (1992-07-01), Carter et al.
patent: 5362325 (1994-11-01), Shiraishi et al.
patent: 5640010 (1997-06-01), Twerenbold
patent: 5643540 (1997-07-01), Carter et al.
patent: 5827531 (1998-10-01), Morrison et al.
patent: 6015104 (2000-01-01), Rich, Jr.
patent: 6099864 (2000-08-01), Morrison et al.
patent: 6103271 (2000-08-01), Morrison et al.
patent: 6214300 (2001-04-01), Morrison et al.
patent: 6355217 (2002-03-01), Kiefersauer et al.
patent: 6387399 (2002-05-01), Morrison et al.
patent: 6406903 (2002-06-01), Bray et al.
patent: 6409832 (2002-06-01), Weigl et al.
patent: 6458332 (2002-10-01), Ooshima et al.
patent: 2001/0006679 (2001-07-01), Morrison et al.
patent: 2001/0026812 (2001-10-01), Morrison et al.
patent: 05115922 (1994-11-01), None
patent: WO 01/75415 (2001-10-01), None
Crystal Growth Techniques Data Sheet,Hampton Research.
Hanging Droplet Method for Protein Crystallization, p. 1, http://people.cornell.edu/pages/cmf5/CrystalFold/HangDrop.html.
NASA Fact Sheet, “Advanced Protein Crystallization Facility (APCF)”, http://www1.msfc.nasa.gov/NEWSROOM/background/facts/apcf.html.
NASA Fact Sheet, Protein Crystal Growth (PCG) Single-locker Thermal Enclosure System (STES) housing the Protein Crystallization Apparatus for Microgravity (PCAM), http://www1.msfc.nasa.gov/NEWSROOM/background/facts/pcgstet.html.
NASA Recommendations, “Future Biotechnology Research on the International Space Station”,Executive Summery, National Academy Press, 2000 pp. 1-9.
NASA, “What is Protein Crystallizaation”,Alabama Space Grant Education Outreach, http://www.uah.edu/ASGC/educationoutreach/crystallization.htm.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Protein temperature evaporation-controlled crystallization... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Protein temperature evaporation-controlled crystallization..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Protein temperature evaporation-controlled crystallization... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3825009

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.