Protein structures and protein fibres

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Reexamination Certificate

active

07045537

ABSTRACT:
This invention relates to protein fiber formation and in particular to methods of producing protein fibers to form a protein structure comprising a plurality of first polypeptide units arranged in a first polypeptide strand and a plurality of second polypeptide units arranged in a second polypeptide strand, the strands preferably forming a coiled coil structure, and in which a first polypeptide unit in the first strand extends beyond a corresponding second polypeptide unit in the second strand in the direction of the strands.

REFERENCES:
patent: 5712366 (1998-01-01), McGrath et al.
patent: WO 96/11947 (1996-04-01), None
Shuichi Kojima et al.; “Fibril Formation by an Amphipathic Alpha-Helix-Forming Polypeptide Produced by Gene Engineering”, Proceedings of the Japan Academy Series B Physical and Biological, vol. 73, No. 1, 1997, pp. 7-11.
W.A. Petka et al., “Reversible Hydrogels From Self-Assembling Artificial Proteins”, Science, AAAS. Lancaster, PA, US, vol. 281, Jun. 17, 1998, pp. 389-392.
W.D. Kohn et al., “De Novo Design of Alpha-Helical Coiled Coils and Bundles: Models for the Development of Protein-Design Principles”, Trends in Biotechnology, NL, Elsevier, Amsterdam, vol. 16, No. 9, Sep. 1998, pp. 379-389.

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