Protein stabilized oil-in-water emulsions

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Web – sheet or filament bases; compositions of bandages; or...

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424444, 424449, A61L 1500

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active

061068551

ABSTRACT:
Stable oil-in-water emulsions are prepared by mixing oil, water and an insoluble protein at high shear. By varying the amount of insoluble protein the emulsions may be made liquid, semisolid or solid. The preferred insoluble proteins are insoluble fibrous proteins such as collagen. The emulsions may be medicated with hydrophilic or hydrophobic pharmacologically active agents and are useful as or in wound dressings or ointments.

REFERENCES:
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patent: 3823212 (1974-07-01), Chvapil
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patent: 4670550 (1987-06-01), Bleeker et al.
Collagen Sponge: Theory and Practice of Medical Applications; J. Biomed. Mater. Res., vol. 11, pp. 721-741 (1977), Milos Chvapil.
Collagen Biomaterials Characteristics and Applications; JALCA, vol. 80, pp. 195-212 (1985), Alain Huc.
Derwent WPI Abstract JP-A-55082621, Jun. 21., 1980.
Derwent WPI Abstract JP-B-85034923, Jun. 25, 1980.
Eaglstein et al. (1980). J. Inv. Dermatol. 74(2) : 90-91.

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