Protein specific for cardiac and skeletal muscle

Details Protein specific for cardiac and skeletal muscle Protein specific for cardiac and skeletal muscle

2006-05-23

2008-09-16

Saidha, Tekchand (Department: 1652)

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

C435S252300, C435S252320, C435S320100, C536S023100

Reexamination Certificate

active

07425615

ABSTRACT:
The present invention relates to a muscle-specific protein, Ozz, and nucleic acids encoding the protein, that regulates development and function of muscle cells. The invention further relates to muscle-specific regulated expression of the protein, and of heterologous genes under control of the same regulatory sequences. In a specific example, a murine Ozz protein of 285 amino acids is preferentially expressed by a 1.0 kb mRNA in heart and skeletal muscle. This protein shares significant homology with neuralized proteins, and associates with a number of muscle proteins, including β-catenin.

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