Protein serine kinase, SRPK1

Details Protein serine kinase, SRPK1 Protein serine kinase, SRPK1

1994-06-22

1996-09-24

Patterson, Jr., Charles L.

Chemistry: molecular biology and microbiology

Spore forming or isolating process

435194, 4352523, 43525233, 43525411, 536 232, C12N 1554, C12N 1563, C12N 115, C12N 121, C12N 510

Patent

active

055590195

ABSTRACT:
A novel serine protein kinase, SRPK1, having a molecular weight of about 92 kD and phosphorylating the SR family of splicing factors in a cell-cycle regulated manner is described. Polynucleotide and polypeptide sequences for SRPK1 are provided as well as methods for modulating splicing and alternative splicing of precursor mRNAs.

REFERENCES:
Woppman et al. (1993) Nucleic Acids Research 21: 2815-2822.
Gui et al. (1994) Nature 369: 678-682.
Gui et al. (1994) Proc. Nat. Acad. Sci., USA 91: 10824-10828.

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