Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Amino acid sequence disclosed in whole or in part; or...
Patent
1992-10-21
1997-01-28
Wax, Robert A.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Amino acid sequence disclosed in whole or in part; or...
530324, 530350, 43193, A61K 39002, C07K 1400, C12N 910
Patent
active
055975704
ABSTRACT:
The present invention relates to the development of a vaccine against schistosomiasis. It relates to a protein which includes the epitopes of the p28 protein, a poxvirus containing a gene coding for the said protein, a cell incorporating a vector for the expression of the said protein, a method for preparing the said protein, a DNA sequence coding for the p28 protein, a pharmaceutical composition, antibodies raised against the said protein and their application by way of diagnostic agents for schistosomiasis.
The present invention also relates to the application of the said protein by way of an agent possessing glutathione S-transferase activity.
REFERENCES:
patent: 4150107 (1979-04-01), Enders et al.
patent: 4384992 (1983-05-01), Capron et al.
patent: 4396600 (1983-08-01), Messineo et al.
patent: 5051254 (1991-09-01), Strand
Cordingley et al, Molecular and Biochemical Parasitology, 18 (1986) 73-88.
Balloul et al, Molecular and Biochemical Parasitology, 17 (1985) 105-114.
Taylor et al, Chem. Abs. 101, No. 21, 184923.
Aronstein et al, Chem. Abs. Nos. 103, 19, 158710m.
Iino et al, Chem. Abs. 105, No. 13, 1097805.
Knight et al, Chem. Abs. 104, No. 19, 1628629.
Smith et al, Proc. Natl. Acad. Sci. USA (1986) 83 (22), 8703-7 (CA 106(5):28407u).
Davern et al, Immunol. Cell Biol, (1987) 65(6), 473-82, (CA 109 (1), 4955q).
Cordingley et al; Molecular and Biochemical Parasitology, 18 (1986) 73-88; "Identification by Message Selection of cDNA Clones Encoding Antigens of `Schistosoma Mansoni`".
Balloul et al; Molecular and Biochemical Parasitology, 17 (1985) 105-114; "In Vitro Synthesis of a 28 Kilokalton Antigen Present on the Surface of the Schistosomulum of `Schistosoma Mansoni`".
J. M. Balloul et al. "Molecular Cloning of a Protective Antigen of Schistosomes" Nature 326:149-153 (Mar. 1987).
Taylor et al. Chem Abs 101, No. 21, 184923 (Nov. 1984).
Aronstein et al. Chem Abs 103, No. 19 158710m (Nov. 1985).
Iino et al. Chem Abs 105 No. 13 109780s (Sep. 1986).
Knight et al. Chem Abs 104 No. 19 162862a (May 1986).
Smith et al., Proc. Nat'l Aca. Sci (USA) 1986 83(22), pp. 8703-8707, [CA 106(5): 28407 u].
Davern et al., Immunol Cell Biol. (1987), 65(6) pp. 473-482, [CA 109(1), 4955g].
Taylor et al, Chem. Abs. 101, No. 21, 184923 (Nov. 1984).
Aronstein et al, Chem. Abs. 103, No. 19, 158710m (Nov. 1985).
Iino et al, Chem. Abs. 105, No. 13, 1097805 (Sep. 1986).
Knight et al, Chem. Abs. 104, No. 19, 1628629 (May 1986).
Chem. Abs., 101, No. 21, 184923, Taylor et al (Nov. 1984).
Chem. Abs., 103, No. 19, 158710m, Aronstein et al (Nov. 1985).
Chem. Abs. 105, No. 13, 109780s, Iino et al (Sep. 1986).
Chem. Abs. 104, No. 19, 162862a, Knight et al (May 1986).
Balloul Jean-Marc
Capron Andre
Grzych Jean-Marie
Kieny Marie-Paule
LeCocq Jean-Pierre
Prouty Rebecca
Transgene S.A.
Wax Robert A.
LandOfFree
Protein recognized by antibodies raised against native P28 of sc does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Protein recognized by antibodies raised against native P28 of sc, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Protein recognized by antibodies raised against native P28 of sc will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-940117