Protein product, process for making it and pharmaceutical compos

Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Genetically modified micro-organism – cell – or virus

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424 85, 424 88, 260112R, 260112B, 514 6, 514 8, A61K 3936, A61K 3900, A61K 4502, A61K 3700

Patent

active

045592306

ABSTRACT:
New product consisting of glycoprotein having a molecular weight of about 14,000 and an isoelectric point of about 4.6, its absorption spectrum having an absorption of .epsilon.=0.12 units of optical density (O.D.) at 280 nm for an aqueous solution of 1 mg (dry weight) per ml of water. This product has immunoregulating properties and is useful in allergic therapeutic composition.

REFERENCES:
Chemical Abstracts, vol. 88, 1978, No. 87459v, p. 354, Topping, M. D. et al., "Fractionation of Cocksfoot . . . by Preparative Isoelectric Focusing".
Chemical Abstracts, vol. 89, 1979, No. 105669r, p. Lowenstein, H., "Immunological Partial Identity . . . Four Grasses".
Chemical Abstracts, vol. 95, 1981, No. 166836p, p. 536, Williams, S. E. et al., "Comparison of Allergenic Extracts . . . Focusing".
Chemical Abstracts, vol. 95, 1981, No. 76296h, p. 378, Hari, V., "A Method for the Two-Dimensional Electrophoresis of Leaf Proteins".
"McGraw-Hill Dictionary of the Life Sciences," pp. 354 and 676.
Journal of Chromatography, 150, (1978), 17-44, "Chromatofocusing: Isoelectric Focusing on Ion-Exchange Columns", Sluyterman et al., pp. 17-44.
Biochimica et Biophysica Acta, 295, (1973), "Isoelectric Focusing in Layers of Granulated Gels", Bertold J. Radola, pp. 412-428.

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