Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Patent
1994-01-31
1998-08-04
Jacobson, Dian C.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
435193, 4353201, C12N 910, C12N 1554
Patent
active
057895589
ABSTRACT:
The present invention relates, in general, to a protein prenyltransferase and, in particular, to protein geranylgeranyltransferase (GGTase-I) and to a nucleic acid sequence encoding same. The invention also relates to methods of producing GGTase-I and geranylgeranyl modified polypeptides. The invention further relates to a method of screening compounds for the ability to alter GGTase-I activity.
REFERENCES:
FASEB J. 7:A1042 (1993).
Lee, C. C. et al. Science 239:1288-1291 (1988).
Zhang, F.L. et al. J.Biol.Chem. 269(5):3175-3180 (1994).
Casey Patrick J.
Diehl Ronald E.
Kohl Nancy E.
Omer Charles A.
Zhang Fang
Daniel Mark R.
Duke University
Jacobson Dian C.
Merck & Co. , Inc.
Muthard David A.
LandOfFree
Protein prenyltransferase does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Protein prenyltransferase, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Protein prenyltransferase will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1178421