Protein (PP.sub.17), a process for concentrating and isolating i

Details Protein (PP.sub.17), a process for concentrating and isolating i Protein (PP.sub.17), a process for concentrating and isolating i

1983-07-29

1984-08-28

Schain, Howard E.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260112B, 424 85, 424 88, 424105, 436543, C07G 700, A61K 3542, A61K 3550, A61K 39395

Patent

active

044683456

ABSTRACT:
The protein PP.sub.17, which has (a) an electrophoretic mobility in the range between .beta..sub.1 - and .alpha..sub.2 -globulins, (b) an isoelectric point of 5.25.+-.0.20, (c) a sedimentation coefficient S.sub.20.sup.o, w of 2.7.+-.0.1 S, (d) a molecular weight, determined in polyacrylamide gel containing sodium dodecyl sulfate (SDS), of 38,000.+-.2,000, (e) an extinction coefficient E.sub.1cm.sup.1% (280 nm) of 8.5.+-.0.4 and (f) a carbohydrate content of 2.1.+-.0.9% containing 0.3.+-.0.2% of mannose, 0.4.+-.0.2% of galactose, 0.2.+-.0.1% of xylose, 1.0.+-.0.3% of N-acetyl-glucosamine and 0.2.+-.0.1% of N-acetyl-neuramin acid, is described.
A process for concentrating and isolating it and its use are also described.

REFERENCES:
patent: 4041021 (1977-08-01), Bohn
patent: 4254021 (1981-03-01), Bohn et al.
patent: 4348316 (1982-09-01), Bohn
patent: 4368148 (1983-01-01), Bohn
patent: 4402872 (1983-09-01), Bohn

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