Protein polysaccharide 0041

Details Protein polysaccharide 0041 Protein polysaccharide 0041

1998-12-03

2001-03-06

Lankford, Jr., Leon B. (Department: 1651)

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Fungi

C424S093500, C435S071100, C435S072000, C435S256800, C435S261000, C435S911000

Reexamination Certificate

active

06197571

ABSTRACT:

BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to protein polysaccharide 0041 with an immunopotentiating antitumor activity.
According to the present invention, protein polysaccharide 0041 has an immunopotentiating antitumor activity and thus high potency as an antitumor agent and an immunopotentiating substance for various tumors.
2. Description of the Related Art
Conventionally, fruit body of
Agaricus blazei
is regenerated and manufactured by artificially culturing its mycelia, and its dried fruit body is commercialized in a large amount as functional food.
The water extract of the dried fruit body, extracted with hot water, is drunk with the expectation of efficacy such as immunopotentiation.
Preparation of the fruit body of
Agaricus blazei
requires a considerable day and time for regeneration of the fruit body from seed culture of the mycelia, and the productivity is low and its price for commercialization is consequently high.
There are a large number of
Agaricus blazei
mutants, and their efficacies of the biological activities are rather diverse and generally not uniform as a whole.
The object of the present invention is to search cultured mycelia of
Agaricus blazei
, not for the generation of the fruit body, but for a new strain of
Agaricus blazei
excellent in efficacy and stable productivity and to isolate a new immunopotentiating substance from the cultured mycelia.
SUMMARY OF THE INVENTION
The present invention provides a biologically pure culture of
Agaricus blazei
strain FERM BP-6210 and a method of producing a protein polysaccharide from this strain.
The present invention further provides a protein polysaccharide 0041 produced by this
Agaricus blazei
strain FERM BP-6210.


REFERENCES:
patent: 6093694 (2000-07-01), Fujimiya et al.
patent: WO98/27992 (1998-07-01), None
Patent Abstracts of Japan; Pub. No. 02078630; Inventor: Nakamura Takuji; Date Feb 19, 1990.
Patent Abstracts of Japan; Pub. No. 02211847; Inventor: I to Hitoshi; Date Aug. 23, 1990.

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