Protein polyligands joined to a stable protein core

Details Protein polyligands joined to a stable protein core Protein polyligands joined to a stable protein core

1992-08-20

1997-09-30

Ziska, Suzanne E.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

4352402, 536 2351, 536 2353, 536 234, 536 231, C12N 1500, C12N 500, C12P 2106, C07H 2104

Patent

active

056724861

ABSTRACT:
Stable polyligands are provided by preparing fused proteins, where the fused protein comprises a ligand at one terminus and a subunit of a multimeric unit protein at the other terminus, where the fused protein is able to assemble to provide a polyligand. The polyligands find use in modulating physiological processes by inhibiting ligand induced signal transduction by surface membrane protein receptors and/or in the case of .mu. chain use, by complement mediated killing or any other effector functions. The molecule may be composed solely, of human components to avoid an immune response by the recipient.

REFERENCES:
patent: 4935352 (1990-06-01), Koichi et al.

Affiliated with

Also associated with

Rating

Protein polyligands joined to a stable protein core does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Protein polyligands joined to a stable protein core, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Protein polyligands joined to a stable protein core will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2256032