Protein microspheres and methods of using them

Details Protein microspheres and methods of using them Protein microspheres and methods of using them

1994-06-17

1997-10-21

Lovering, Richard D.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

264 432, 264 46, 424484, 424485, 424486, 427 214, 427 221, 42721331, 4284022, 42840221, 42840224, 514866, 514963, 514965, A61K 952, B01J 1312

Patent

active

056793774

ABSTRACT:
Biodegradable, protein microspheres for in vivo release of a biologically active agent, as well as agricultural and environmental applications. The microspheres can be administered orally, intravenously, or subcutaneously for subsequent release. By selecting particular size ranges and the specific protein used to form the microsphere, it is possible to target the microspheres to a cell types such as macrophages, or to effect localized absorption of the microspheres to regions such as the mucosal membranes of the mouth, gastrointestinal tract, or urogenital areas. Larger forms of the microspheres can also be made using standard techniques of the desirable degradation properties.

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