Protein markers for diagnosing stomach cancer and the...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

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Reexamination Certificate

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07892761

ABSTRACT:
The present invention relates to protein markers for diagnosing stomach cancer and a diagnostic kit using the same, more precisely protein markers screened by two-dimensional gel electrophoresis and bioinformatics and a diagnostic kit using the same. The markers of the invention can be effectively used for diagnosing stomach cancer and evaluating the extent of progress of the cancer by confirming the expression levels of those marker proteins whose expressions differ in stomach cancer patients from in normal healthy people.

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patent: 1394182 (2004-03-01), None
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QY He, et al., “Diverse proteomic alterations in gastric adenocarcinoma”, Proteomics Oct. 2004 vol. 4(10), pp. 3276-3287.
JS Jang, et al., “The differential proteome profile of stomach cancer: identification of the biomarker candidates”, Oncol. Res. 2004 vol. 14(10), pp. 491-499.
J.S. Kim, “Identification of a possible marker protein for gastric cancer by proteomic analysis”, Master Thesis of College of Pharmacy, Choong-Ang University (Korea), 2002.
J.W. Ryu, et al., “The proteomics approach to find biomarkers in gastric cancer”, J. Korean Med. Sci. 2003 vol. 18, pp. 505-509.

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