Protein kinase inhibitors and methods for identifying same

Details Protein kinase inhibitors and methods for identifying same Protein kinase inhibitors and methods for identifying same

2011-03-08

2011-03-08

Ha, Julie (Department: 1654)

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

8 to 10 amino acid residues in defined sequence

C530S300000, C530S323000

Reexamination Certificate

active

07902330

ABSTRACT:
Inhibitors of protein kinase C (PKC)α, PKCδ and PKCζ are provided which are selective for those PKC isotypes. Combinatorial libraries for identifying protein kinases are also provided, as are methods of identifying protein kinases using those libraries. Additionally, methods of treating a mammal having a deleterious condition, where the condition is dependent on a protein kinase for induction or severity, are provided. Methods of inhibiting protein kinases are also provided.

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