Protein kinase inhibitor

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ester doai

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Details

514523, 514525, A61K 3121, A61K 3126, A61K 31275

Patent

active

058542850

ABSTRACT:
A compound of the formula I ##STR1## wherein A and C are independently H, alkyl of 1-6 carbon atoms, hydroxy, or alkoxy of 1-6 carbon atoms;

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Novogrodsky, A., et al. (1994) "Prevention of Lipopolysaccharide-Induced Lethal Toxicity by Tyrosine Kinase Inhibitors," Science 264:1319-1322.
Shiraishi, T., et al. (1987) "Specific Inhibitors of Tyrosine-Specific Protein Kinases. I. Synthesis and Inhibitory Activities of .alpha.-Cyanocinnamamides," Chem. Pharm. Bull. 36:974-981.
Tan, C.M., et al. (1995) "Oxidant Stress Enhances Adenylyl Cyclease Activation," Circulation Research 77:710-717.
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