Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1996-11-18
1998-01-20
Shah, Mukund J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
540469, 514185, A61K 31395, C07D41900
Patent
active
057101450
ABSTRACT:
This invention provides novel bis-indolylmaleimide macrocycle derivatives of the formula: ##STR1## and solvates thereof. The invention further provides the preparation, pharmaceutical formulations and the methods of use for inhibiting Protein Kinase C in mammals.
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Engel Gary Lowell
Farid Nagy Alphonse
Faul Margaret Mary
Jirousek Michael Robert
Richardson Lori Ann
Boone David E.
Caltrider Steven P.
Eli Lilly and Company
Shah Mukund J.
Sripada Pavanaram K.
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