Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1999-12-07
2000-09-12
Raymond, Richard L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514185, 514410, 540469, A01N 4300, A61K 31555, C07D26722
Patent
active
061178616
ABSTRACT:
This invention provides novel bis-indolylmaleimide macrocycle derivatives of the formula: ##STR1## and solvates thereof. The invention further provides the preparation, pharmaceutical formulations and the methods of use for inhibiting Protein Kinase C in mammals.
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Engel Gary Lowell
Farid Nagy Alphonse
Faul Margaret Mary
Jirousek Michael Robert
Richardson Lori Ann
Caltrider Steven P.
Darkes Paul R.
Eli Lilly and Company
Raymond Richard L.
Truong Tamthom N.
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