Protein interaction difference mapping

Details Protein interaction difference mapping Protein interaction difference mapping

2008-03-25

2008-03-25

Lam, Ann Y. (Department: 1641)

Chemistry: analytical and immunological testing

Involving an insoluble carrier for immobilizing immunochemicals

C435S004000

Reexamination Certificate

active

10626493

ABSTRACT:
This invention provides methods and materials for mapping interaction characteristics between components of a multicomponent biological complex. The methods involve capturing a multicomponent complex on a solid support and washing the support with a series of elution washes forming a gradient of solute concentrations, and determining whether a particular elution wash eluted a particular component.

REFERENCES:
patent: 5234811 (1993-08-01), Beutler et al.
patent: 5571729 (1996-11-01), Nakamura et al.
patent: 5719060 (1998-02-01), Hutchens et al.
patent: 6225047 (2001-05-01), Hutchens et al.
patent: 6265715 (2001-07-01), Perreault et al.
patent: 6548021 (2003-04-01), Church et al.
patent: 6599728 (2003-07-01), Morin et al.
patent: WO 01/88528 (2001-11-01), None
patent: WO 03/042233 (2003-05-01), None
Koch, Christian, et al., “A role for Ctr9p and Paf1p in the regulation of G1cyclin expression in yeast;” 1999;Nucleic Acids Research; vol. 27; No. 10; pp. 2126-2134.
Lalev, Atanas, et al., “Ribosomal RNA Maturation in Schizosaccharomyces pombe is Dependent on a Large Ribonucleoprotein Complex of the Internal Transcribed Spacer 1;” 2000;Journal of Microbiology; vol. 302; pp. 65-77.
Nelson, Thomas J. et al., “Isolation of Protein Subpopulations Undergoing Protein-Protein Interactions;” 2002;The American Society for Biochemistry and Molecular Biology, Inc.; pp. 253-259.

Affiliated with

Also associated with

Rating

Protein interaction difference mapping does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Protein interaction difference mapping, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Protein interaction difference mapping will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3933038