Protein having PGE2 synthase activity and use thereof

Details Protein having PGE2 synthase activity and use thereof Protein having PGE2 synthase activity and use thereof

2007-01-30

2007-01-30

Slobodyansky, Elizabeth (Department: 1652)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing a prostaglandin nucleus

C435S189000, C514S573000

Reexamination Certificate

active

10182233

ABSTRACT:
A single protein which is the substance of the PGE2 synthesis activity in brain soluble fractions of LPS administered rats has been purified and identified. The protein has an activity of synthesizing PGE2 from PGH2, and further, has an activity of synthesizing PGE2 from arachidonic acid in combination with COX.

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