Protein having PDZ domain sequence

Details Protein having PDZ domain sequence Protein having PDZ domain sequence

2006-02-21

2006-02-21

Mertz, Prema (Department: 1646)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

C530S350000, C435S069100, C435S471000

Reexamination Certificate

active

07001728

ABSTRACT:
While analyzing changes in gene expression by TNFα in umbilical vascular endothelial cells, a gene showing enhanced expression due to stimulation with TNFα was isolated. After screening with this gene as a probe, a gene encoding a protein was isolated. Analysis of the protein encoded by this isolated gene revealed that this novel protein has never been reported and has a PDZ domain in its molecule that plays an important role in protein—protein interactions.

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