Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1994-01-24
1995-10-31
Patterson, Jr., Charles L.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
530381, 530382, 435 692, C07K 1447, A61K 3817
Patent
active
054630258
ABSTRACT:
A protein having human plasmin inhibiting activity, substantially equivalent reactivity with human plasmin to a human .alpha..sub.2 -plasmin inhibitor derived from plasma, a binding ability to human fibrin about 1/4 to about 1/3 of that of the human .alpha..sub.2 -plasmin inhibitor derived from plasma, and a molecular weight of about 50,000 to about 77,000.
REFERENCES:
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Reed et al. (1990) Circulation 82, 164-168; Abstract Only.
Holmes et al. (1987) Biochemistry 26, 5133-5140.
Christensen et al. (1992) FEBS Lett. 312(1), 100-104.
Tone et al. (1987) J. Biochem. 102, 1033-1041.
Holmes et al. (1987) J. Biol. Chem. 262, 1659-1664.
Sumi et al., "J. Biochemistry" 106 (4) 703-707 (1989).
Sumi et al., "J. Cellular Biochemistry Suppl.", Vol. 0, Part 13A, p. 95 Jan. 1989, Abst. A338.
Aoki Nobuo
Ichikawa Yataro
Muramatsu Masami
Sumi Yoshihiko
Patterson Jr. Charles L.
Teijin Limited
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