Protein having cell growth stimulating action, composition there

Details Protein having cell growth stimulating action, composition there Protein having cell growth stimulating action, composition there

1984-02-28

1986-08-05

Kight, J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

435 68, 435879, 435884, 435839, 435885, 435880, 435849, 435873, 435843, 435842, 424145, 514 6, 530350, C07K 1504, C12P 2100, A61K 3700

Patent

active

046042342

ABSTRACT:
A protein effective in stimulating cell growth activity. The protein has a molecular weight of from 5,000 to about 160,000, is composed predominantly of neutral and acidic amino acids, contains a significant amount of glutamic acid and aspartic acid, and is substantially free of nucleoside phosphotransferase. The protein is useful as wound treatment agent and as promoting agent in the synthesis of DNA. A method of producing the protein and compositions containing the same are also disclosed.

REFERENCES:
patent: 2944940 (1960-07-01), Fischer et al.
patent: 3243345 (1966-03-01), de Jager
patent: 4014992 (1970-03-01), Jolles et al.
patent: 4287184 (1981-09-01), Young
patent: 4292324 (1981-09-01), Jonsson et al.
patent: 4436816 (1984-03-01), Dinka
PNAS, vol. 68(10), 1971 Aryeletti et al., Nerve Growth Factor from Mouse Submoxillery Gland, pp. 2417-2420.
PNAS, vol. 70(4) 1979, Purification of Platelet Derivel Growth Factor, Antoniades et al, pp. 1809-1813.
Physiology Review 60(4) 1980, Physiology of Nerve Growth Factor, Thaenen et al, p. 1302.

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