Protein fragments containing Factor VIII binding domain of von W

Details Protein fragments containing Factor VIII binding domain of von W Protein fragments containing Factor VIII binding domain of von W

1987-05-01

1991-08-27

Kepplinger, Esther L.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Blood proteins or globulins, e.g., proteoglycans, platelet...

530350, 530380, 530381, 530324, 435 696, 435 681, 514 2, 514 8, 514 12, 514 21, C07K 1300

Patent

active

050434292

ABSTRACT:
Peptides which inhibit the binding of von Willebrand Factor to Factor VIII. Monoclonal antibodies capable of specifically binding to the region of von Willebrand Factor containing the Factor VIII binding domain. Improved methods of preparing Factor VIII.

REFERENCES:
patent: 4661471 (1987-04-01), Hawiger et al.
Sadler et al., PNAS, 82, 6394-6398, 1985.
Foster et al., J. Biol. Chem., 262(18), 8443-8446 (1987).
Verweiji et al., EMBOJ, 6(10), 2885-2890, 1987.
Fujimura et al., J. Biol. Chem., 262(4), 1734-1739, (1987).

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