Protein formulations for use at elevated temperatures

Details Protein formulations for use at elevated temperatures Protein formulations for use at elevated temperatures

2011-06-21

2011-06-21

Kemmerer, Elizabeth C (Department: 1646)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

C514S008800, C514S007600, C514S016700, C514S016800, C514S016900, C514S017100, C536S123100

Reexamination Certificate

active

07964561

ABSTRACT:
Liquid formulations of bone morphogenetic proteins are provided for prolonged use at elevated temperatures. More specifically, the invention relates to liquid formulations comprising rhGDF-5, trehalose, and one or more biocompatible excipients that provide stability to the protein for at least 30 days at temperatures up to body temperature.

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