Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Chemical modification or the reaction product thereof – e.g.,...
Patent
1991-09-24
1994-12-06
Kim, Kay K. A.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Chemical modification or the reaction product thereof, e.g.,...
530402, 530403, 530405, 530408, 530409, 530395, 4241941, 42419711, 4242031, 4242441, 4242561, 424831, C07K 1702, C07K 1710, A61K 39385, A61K 39116
Patent
active
053711971
ABSTRACT:
A conjugate immunogen, having polysaccharide moieties derived from bacterial sources, provides a multivalent vaccine with a low protein to polysaccharide ratio. The vaccine reduces complications associated with injection of protein immunogens due to pyrogenic responses, such as swelling and pain, and is particularly suitable for administration to infants.
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Marburg Stephen
Tolman Richard L.
Bencen Gerard H.
Kim Kay K. A.
Merck & Co. , Inc.
Parr Richard J.
Pfeiffer Hesna J.
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