Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1997-10-02
1999-12-21
Priebe, Scott D.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
562 231, 4353201, 435325, 435455, 435458, A61K 4800, C12N 1500
Patent
active
060049448
ABSTRACT:
Secretory gland cells, particularly pancreatic, hepatic, and salivary gland cells, are genetically altered to operatively incorporate a gene which expresses a protein which has a desired therapeutic effect on a mammalian subject. The expressed protein is secreted directly into the bloodstream to obtain therapeutic levels of the protein thereby treating the patient in need of the protein. The transformed secretory gland cells provide long term or short term therapies for diseases associated with a deficiency in a particular protein or which are amenable to treatment by overexpression of a protein.
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German Michael S.
Goldfine Ira D.
Rothman Stephen S.
Francis Carol L.
Nguyen Dave Trong
Priebe Scott D.
The Regents of the University of California
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