Protein crystallisation method

Details Protein crystallisation method Protein crystallisation method

2003-07-29

2008-12-30

Kunemund, Robert M (Department: 1792)

Single-crystal, oriented-crystal, and epitaxy growth processes;

Processes of growth from liquid or supercritical state

Having growth from a solution comprising a solvent which is...

C117S069000, C117S070000, C117S925000, C117S926000, C117S927000

Reexamination Certificate

active

07470324

ABSTRACT:
A method for the crystallization of macromolecules in a three-phase system using a vessel containing a lower aqueous phase, a middle phase and an upper hydrophobic phase having a lower density than that of the lower aqueous phase, wherein an aqueous solution of the macromolecules is added to the middle phase to form a fourth phase, followed by incubation.

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patent: 2001/0002261 (2001-05-01), Morrison et al.
patent: 2006/0090644 (2006-05-01), Sirkar
patent: 07053738 (1995-02-01), None
patent: WO 01/88231 (2001-11-01), None
Mayer et al. Journal of Molecular Biology, 1999, vol. 292, pp. 871-891.

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