Protein crosslinking reagents cleavable within acidified intrace

Details Protein crosslinking reagents cleavable within acidified intrace Protein crosslinking reagents cleavable within acidified intrace

1988-06-01

1991-11-19

Russel, Jeffrey E.

Drug, bio-affecting and body treating compositions

Lymphokine

424 941, 530345, 530389, 530391, 530395, 530397, 530399, 530409, 530410, 435188, 514 21, 548407, 548409, A61K 3944, A61K 3748, C07K 1702

Patent

active

050664905

ABSTRACT:
Crosslinking reagents for amino group-containing compounds are provided, which crosslinkers can be cleaved under mildly acidic conditions. The crosslinkers can be used to crosslink biologically active substances to be delivered to the cells, wherein the crosslinker will be cleaved in the mildly acidic conditions within the cell.

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