Protein containing serum albumin domain

Details Protein containing serum albumin domain Protein containing serum albumin domain

2007-08-07

2007-08-07

Carlson, Karen Cochrane (Department: 1656)

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Reexamination Certificate

active

11044265

ABSTRACT:
A protein produced by gene recombinant technology, including at least one domain selected from domains I, II, and III of serum albumin but having a different structure from that of native albumin; and a method of producing the protein. The protein has an enhanced functional activity or activities selected from among various functional activities or serum albumin including antibacterial activity, antioxidative effect, inflammation inhibitory effect, in vivo substance transporting action, and enzymatic activity.

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Sheffield et al., Modulation of Clearance of Recombinant Serum Albumin by Either Glycosylation or Truncation, Thrombosis Reasearch, 99 (2000), p. 613-621.
Dockal et al., The Three Recombinant Domains of Human Serum Albumin, J. of Biological Chemistry, 274, 41 (1999), p. 29303-29310.

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